May this be an answer?
Restart the immunesystem with your own stemcells?
http://www.diabetesincontrol.com/results.php?storyarticle=4730
Restart the immunesystem with your own stemcells?
I am a strong supporter of research regarding islet regeneration (e.g.Denise Faustman)
End Quoute
Denise Faustman actaully have a drug that stops the imune system to attack the insulinproducing cells (whitch is the case in Type 1 diabetics, as myself). But this is unforturnatilly not the whole solution, because regeneration does not seem to happen if the bloodsugar is not normal for a long period of time. This is unforturnatilly almost impossible to get with the tools diabetics have today. Maby it can be possible with a continous bloodsugarmeasure devise that controls a pump that pumps insulin direct in the blood? Or maby it can be possible with microencapsuled xenotransplantatated insulinproducing cells? Actually there is another problem also that needs to be solved for Faustmans research to be successful, and that is finding a way to measure the effect of the drug, actually that is her current focus to solve that problem and find something like a bloodtest to show the effect of her drug.
Read more about Faustmans research(and a few other projects of intrest) here.http://iacoccafoundation.org/grants_diabetes_research.html
I test my bloodsugar very often, often arround 10-20 times a day. This is becoming a bigger problem because i can not get all the testing-strips needed for this. The reason i cant get all the testing strips i need is because of the cost (almost 1$ for one strip), which makes up to 20$ a day cost for me. The market for testing strips are totally nuts and companies make to mutch money on this. The reason this is a problem is that it is the very same companies that are researching for alternatives to disposable testing strips, but why should they put that mutch effort in removing their biggest income by selling testing strips?
First i took a HBA1C-test to find out what my average bloodsugar had been the latest few weeks. It turned out to be 5.5, which was a lot lower than i had expected. If you look at the graph in my previus post, you can se that the average value of my testings is 9.3 mmol/l, which is a lot higher. Then offcourse you should be aware that HBA1C is not directly translatable to an avaragevalue of bloodsugar in mmol/l, but it should be somewhere in that area. In fact the HBA1Cvalue is a bit lower, but not that much that this reading told me. This in fact is good news, and underlines my theory that my high average value is closely related to the fact that i test frequentily when i have high bloodsugar. I do this to be sure that my insulincompensation i sufficient, and that the bloodsugar starts to turn down to more acceptable levels (<12).
Hello!


It has been a while since my last post here.
The new programming worked out very good. I have had quite good values all the time, i still have up to around 12 at night time, but i will give it some more time before i alter it any further. One good thing is that i don't sleep that many minutes in a row because of the new baby so i get lots of chances to do nightly testing so i can be sure that i don't get any lows during night time. Today i had a bit of problems with the infusion again. This time i took a bath with my daughter at the morning. I disconnected the pump when i was in the bath, but i left the infusion needle in. When i reconnected myself again to the pump the connection did not work anymore. I found that out after lunch when my blood sugar rose very quickly. But this time i knew what the problem was and could change the infusion needle right away. Next time i will remove the needle when i take a bath, and change it to a new one afterwards.
Now i have reprogrammed the pump to give me some more insulin during nighttime. I was not able to get in touch with the hospital to discuss this as i wanted, but this was really necessary.

The last days i have had some low blood sugar readings (~4) around 8PM, so therefore i have started to eat a sandwich around that time. I always have OK blood sugar before i go to bed, but i have discovered that my blood sugar between 1AM and 6AM almost always is very high (16-20). Maybe i need more insulin during night time, or maybe i get so low that these nightly highs are and effect of that. I will try to get in touch with the hospital again to discuss this.
At 9AM this morning we will go to the maternity ward. Maybe we will be parents for the 2nd time today! ;o) We have the bag packed, and we have called my wife's mother who will soon come over here to take care of our 2 year old daughter, while we are at the maternity ward. Maybe i can't write for a few day depending on how long this will take. Take care, and keep your fingers crossed for us!
A possible complication of diabetes is problems with the eyes, you can read more about why this can happen here. A few years ago many diabetics actually eventually got blind from diabetes, but now days that is extremely rare. The reason it is very rare now days is because now days every diabetic screen their eyes regularly. If changes are found and they have gone far they can set in laser treatment in time so almost no one needs to get blind from diabetes anymore. The last time they scanned my eyes they found some diabetic changes in my eyes, so today it was to do a new screening again. What they do at these eye screenings is that they drop a fluid in the eyes that enlarges the pupils so that they almost cover all eye. Then they take photographs of the eyes, in which they get a clear picture if everything looks OK. Today luckily for me it looked like it was less diabetic changes than the last time, this means that it is going in the right direction and no laser treatment is necessary. The fluid affects the eyes for about 5-12 hours and makes the eyes VERY sensitive for light. Therefore i still have a lot of trouble to see the computer screen right now. Because everything looked better, i will screen my eyes again the next time in about 8 months.
I got high blood sugar again in the middle of the night, i gave myself some more bolus and then it worked for a while again. But today it stopped to work again, so now i have changed everything (insulin container, tubing, infusion set) again. I noticed when i changed my insulin container that i had filled them to much, so i had to release some insulin from the container before i was able to load it. Now i am back to infusion in my belly again, i hope it will work this time. I guess that i might have to accept that i will need to change to infusion site every day. Everyone i have talked to at the hospital, says that i should not have to do that. But what other conclusion can i draw from this?
Now i woke up again at 1:30AM with 21 in blood sugar. This time no alarm from the pump. What could it be that is causing this? I have just given myself 4IE bolus, but i have no ketones so far. Because it is weekend now, there is no one to call and ask right now unforturnately. But i guess i must call the diabetic center again on Monday. This is beginning to be so annoying now, i really want it to just work right now when we are soon having a baby and all...
Now i have signed up for the new job, i think it will be a good job for me. The pump wear worked fine, the only problem was that i was not able to see the pump. My blood sugar values have been OK all day, since i woke up. Now i guess i am finally ready for my next daughter, when ever she wishes to arrive.
At 3.15AM I'm Finally down to 11.0, and this means that the new infusion should work. Back to sleep again. I had to get up 7AM to be able to get to the day nursery in time with my daughter. At least the blood sugar value this morning was OK. But i am dead tired.
The pump just woke me up at 1AM, with an alarm for occulsion again...
Today my blood sugar values are still OK. This was my last day at the hospital, from now on i will only have phone contacts with the hospital regularly, and visit them about 4 times a year if nothing goes wrong. Today they had a lecture about diabetes. Unfortunately for me almost every information they had was about type II. Diabetes type II is a very different disease than Type I as i have. Because most diabetic have Type II, most articles in the media is about Type II as well. That is quite understandable. But i find it very disturbing every time someone i know who knows that i have diabetes tells me, that they have read this or that in a newspaper. Mostly the article says it is about diabetes, but the article only relates to Type II, but off course it doesn't say so. Every time this happens i have to explain that this information does not apply to me. A lot of Type II patients have overweight problems and also high blood pressure, while i have a BMI around 21, and have a very low blood pressure. Actually i think the best would be if Diabetes Type I would be called something else, because it actually is a very different disease than Type II. Type I is a autoimmune disease, where the body's immunsystem attacks the insulin producing pancreas and destroys them, in type II on the other hand the pancreas still produce insulin but not enough to keep the patients blood sugar on a reasonable level. Type II is mostly at least at first treatable with pills and/or lifestyle changes, while Type I always require insulin injections.
Finally it seems like everything is working. Today my values have been nearly to OK, 3.7 - 10.5. Therefore i can now begin to think a bit about the next steps, such as variation in insulin/hour during different times of the day. I think that i will need 0.7 IE/h during daytime. During night i think i will need some less insulin, so therefore i will try 6.5 this night. The next time i will change my infusion site, i will chose some alternate location such as my buttock. Hopefully i will by alternating locations not get such many bad infusion sites as i have had so far. Today we have also packed our bag to the maternity ward, because our daughter may come any time now...
This day started out pretty good. From early morning until 4PM my blodsugar where quite OK, 3.6 - 6.2 . Unforturnately something happened with my infusion site again, and my bloodsugar started to rise to 15.1 at most. Therefore I changed my infusion site again, and gave myself some NovoRapid by insulinpen to be sure. The old site looked all OK, but i could feel some tension around the site. Could it be that the insulin gets stuck under my skin after some time with the same site? This time i guess the the needle is not the problem. This I will discuss tomorrow when I am back at the hospital. To night I will need to do some extra testing before I go to bed to make sure that the new site works this time.
Yesterday was my daughters two-year birthday, and she just loved all her gifts. Especially the helter-skelter. A very happy day.
Today i am reconnected again to my pump. This time with a new infusionset, made of steel. So hopefully no more problems with my infusion sites. The bad thing with my new infusionset is that if i disconnect myself from the pump, i still have 10cm of rubber tube hanging from my belly. This was not the case with the other one. But i guess i cant have it all...
One bottle of insulin is enough for about three containers, and i had half a container from earlier. Therefor i now have 5 containers just prepared in my refridgerator. I guess it may be more handy to have them made in advance so that i will have less tangle when its time to change.
Wednesday was a bad day for me unforturnately. When i got home from the hospital i started to feel a bit strange in my stomach. I checked my blood sugar as usual, it was 8 which is OK. Then went to pic up my daughter at the day nursery. On the way home again i started to feel a bit more strange in the stomach, and just before dinner i tested again. Now the meter read 17.6!!!, not very good.
I checked the infusionset, and this is what it looked like when i took it off me. So i attached another infusionset and gave me some bolus. I called the doctor and ask what he thought of it. He told me to eat even though the high blood sugar. He also told me that ketones is not only from high bloodsugar but also from lack of energy from food. Ketones is what you get when you starve. So i ate, but shortly after my meal i started to feel real bad in my stomach, and started to throw up everything again. This kept on all night, until i had to call the doctor again. He thought this was a virus, and at this point i only had 0.3 i ketones which is not a cause for throwing up food. Therefor he told me to hold out a bit. So i did, but i threw up all night until i couldnt even keep a tablespoon of water without throwing up. Then i went in to the hospitals emergency ward. There they did a lot of tests and shipped me to the diabetic care center in the hospital. At that point my pumptreatment stopped for this time, after realising that the new infusionset did not work either. I had some troubles with ketones at the hospital as a complication of the infection, so they kept me for two nights for observation. I just got out of the hospital now, and I'm back on my insulinpen treatment again for now. The most probable cause of my stomach illness was the food i got at the hospital. That in combination with bad infusionsets stopped me from getting on the pump this time.The night was OK, with values around 11 at 2AM, also 6AM i had 9 which must be OK during the circumstances. What now again puzzled me a bit is the reading right before breakfast at 7AM, which was 6.4. Understand me right, this is a good value, i just don't understand why the trend is sinking so fast without any dosing of insulin. Therefore i took only 2IE with my breakfast instead of 3-4 as usual.
Finally i am now connected to the pump. The picture is of my stomach, where the plastic connection is inserted. The day started with a brief introduction of the main functions of the pump, and calculation of my insulin intake per hour. i started on 0.5 IE/h but later i increased it to 0.6. After the introduction i connected the pump, about 10AM, and got started right away. We also tested my HBA1C, which was quite OK, it was 5.6 which is almost what to expect from a non diabetic person. After this there where some time for some more blood sugar testing,it was quite fair, 8.8. Then i got to eat some lunch, and after lunch i was supposed to do some more testing and then finally meet the doctor. The doctor gave me some information about the risk with diabetic ketoacidosis (DKA), and told me that i probably will increase my insulin/hour intake to 0.7IE tomorrow. After that the first day at the hospital was over. When i got home at 4PM i tested my Blood glucose to 11.1. Which was a bit high, but that was just about what i should expect. I tested again at 4:20PM now it was 9.3, strangely enough. Then went to pic up my daughter at the day nursery. The next test just before dinner, puzzled me quite a bit, it was at 5:10PM and i expected something like 8. The meter read 3.4!!! so therefore i ate one extra sandwich with my dinner and took only 3IE for bolus, instead of 4IE. I called the doctor and asked what he thought of this, but he could not explain it. He said that maby there could still be some lantus effective in me. Even more strange was the next value 1.5 hours after dinner. This value should almost certainly be high, but my meter read 2.8!!! Therefore i ate some extra food and drank a glass of juice. I will discuss this i more detail with my doctor tomorrow. But hopefully tomorrow i will get more predictable values. I will also need to do some more testing during the night, i hope those will be OK. Tomorrow i will meet an dietitian to discuss my food intake.
As i wrote in my last post, i have been thinking a bit about how my last lantus injection will influence the first day of my pumpstart. Lantus is a insulin that is supposed to work for 24 hours and work as a basis, to be complemented with mealinjections for every meal i eat. The problem is that lantus does not work 24 hours for everyone, and i am one of those for whom it works less than 24 hours. If this is the case the normal recommendation is to split the lantus dose in two doses with half the amount, and with 12 hours interval, instead of 24.
Right now i have just packed everything i will need tomorrow in the bag on the picture, and that is just about everything there are pictures of in my recent postings, plus some documentation of bloodsugartestings, and documentation of meals. I have no idea how long this pumpeducation will take. In the papers i have recieved it says that i should be there 9am the first day, and that the education will require a minimum of three days. It also says that it will cost me 260 SEK plus lunch every day. From this i draw the conclusion, that i will at least be there from 9am until over lunchtime.
Today have been quite a slow day. I have assembled my daughters 2 year gifts. She will get a threewheeled bike, and a helter-skelter. I wonder a bit about how i will wear the pump, i am not very fond of having it attached to my belt in the leathercase. I guess that would look quite "nerdy". Like a pager. But i guess that will be my smallest problem with the pump. Another thing i wonder a bit about is if it will be difficult the first day, if i still have some Lantus active in my body? I am very uncertain how long Lantus influences my bloodsugar. The only thing im sure of that it does not work 24 hours, like it is supposed to. But then again that will only be a problem on my first day on the pump.
I also need to change my ordinary bloodsugar tester to this one. This one is able to also measure ketones, wich is lot bigger risk to get when only using fastworking insulin. As i will be, when i use a pump. Leftsides the tester is the thing i will use to pick little holes in my fingers to get drops of blood for every testing.
These are my new testingsticks for bloodsugar, and a special callibrations stick that comes with every new package of testingsticks. These are the sticks i use about 10 per day. Unforturnatily these sticks are very expensive, but in sweden we get them for "free". Which actually means that everyone is paying for them with taxes. But the nurses always informs us about how expensive they are every time they subscribe them. Offcourse i am thankful that i get them for "free", but i really dont have much of an alternative. If i dont test that much, its quite a big risk that i get in a coma.
These are the testing sticks for ketones, and the callibration stick for those.
This is the needle and the wireing with wich i am supposed to connect myself to the insulinpump. The wireing is 60 cm long, and the needle is plastic. The blue head, and the metal needle is removed after insterting the needle in my body.
This is the container for the insulin, and the actual insulin wich i am supposed to load the pump with. I will use fastworking insulin called NovoRapid, with my pump.
This is the actual pump i will use, and Skin-Prep to use before connecting the pump to myself. Underneath the pump is a case that came with the pump, wich i dont know yet if i will actually use.
Whoooaa... today i am a bit nervous. I´ve just been to an jobinterview, and i really hope i get that job. That job would suit me perfect. Actually i have a few other job offers right now, but this is the one i hope for.
I have chosen an cozmo insulinpump from deltec. My favorite was really this one: OmniPod . But at södersjukhuset i got to chose between cozmo and the older models from minimed, and animas 1250. I have read a lot about these pumps and my choice fell on the cozmo. I hope won´t regret it, but i feel quite confident that is the best pump that is avalible for me. You can read more about compareing of insulinpumps here: Compare insulinpumps . The downsides with cosmo i have heard of the most, is that the software for communication with laptop. But i guess i can live with that, i wont get the software anyway for a while. In sweden the hospital decides if the patient should get this software or not.
I will begin my pumptraining next monday at södersjukhuset. Today and yesterday, i will write down everything i eat and drink so that i can discuss this with an dietitian at södersjukhuset.
This blog is supposed to be about living with an insulinpump.